Salmon DNA? Do PDRN injections help with skin rejuvenation?

What makes PDRN (aka salmon DNA/sperm injections) so special? And does the treatment work for skin improvement?

PDRN is a natural DNA substance that helps your skin repair itself. It activates the body's regenerative powers, not only improving the appearance of the skin, but also truly renewing it from within.

What exactly is PDRN in salmon DNA?

PDRN stands for Polydeoxyribonucleotide: short DNA fragments, usually extracted from salmon or trout. These fragments activate specific receptors in your skin cells (adenosine A2 receptors), causing:

• blood circulation improves,
• reduce inflammation,
• accelerates wound healing,
• and fibroblasts produce new collagen and elastin.

The result of PDRN: smoother, firmer skin that regains its natural glow. Scientific evidence comes from renowned centers that treat severe burns.

How does PDRN work in the skin?

When PDRN is injected into the skin, it acts as a “messenger” that activates repair. The skin opens up its own blueprint for rejuvenation, so to speak. This leads to:

• improved microcirculation and oxygen supply,
• DNA protection and repair,
• Strengthening of skin structure and firmness.

Your skin becomes vibrant and resilient again, without changing your facial expressions or natural expressions. So this is not a filler.

What is the difference between PDRN and PN?

Both are derived from DNA, but differ slightly in chain length. PDRN is a shorter chain and PN is a longer chain. Their effects differ slightly. PDRN ensures rapid recovery and PN ensures long-lasting hydration and firmness of the skin. Together, they reinforce each other. Many modern skin boosters combine both for maximum effect.

Is PDRN safe?

Yes. PDRN and PN are completely biocompatible and do not pose any risk of vascular or tissue obstruction, unlike fillers. They can be safely combined with microneedling, laser, PRP, or injectables.
Het is een zachte, maar diepwerkende behandeling ideaal voor vrouwen en mannen die natuurlijke resultaten willen zonder downtime.

Why choose PDRN at SkinSurgery?

At SkinSurgery, safety, precision, and natural beauty are paramount. Our doctors combine scientific knowledge with aesthetic insight, ensuring that every treatment subtly enhances your authentic appearance. We listen, observe, and treat with care, so that you can radiate the inner beauty you feel inside.

Frequently asked questions from clients about PDRN treatment

1. How many treatments will I need?

On average, three treatments at intervals of approximately three to four weeks are needed to achieve optimal results. After each session, the effect continues to build: the skin recovers, becomes firmer, and gains more radiance. In some cases, we recommend a maintenance treatment after a few months to prolong the results.

2. Does the treatment hurt?

Most clients find the treatment tolerable. At most, you may feel small pricks or a slight burning sensation during the application of the PDRN. For extra comfort, we always apply an anesthetic cream beforehand to make the treatment as pleasant as possible.

3. When do i see results?

After about two to three weeks, you will notice that your skin looks fresher and feels softer. The radiance, texture, and overall skin quality gradually improve in the weeks that follow. The final result is visible after the full treatment, when cell renewal and collagen production are at their peak.

4. Can I combine PDRN with fillers or Botox?

Yes, PDRN works perfectly as a supplement to existing treatments. It improves skin quality and prolongs the results.

Ready to renew your skin from within?

Schedule a no-obligation consultation at SkinSurgery and discover what PDRN or PN can do for you. We will help you to glow subtly, safely, and naturally at your own pace, with attention to who you are.